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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '79b5ae580060c0334aef50a3e780487298eb8584bf754aaa51a47aad32e46b7a' 
  AND token = 'fMisroF2Y7jwreUAFgkkUhCWrnb6EDOYM7qeZ487aCU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}