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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '265b49a742f1c1ef5eb0ddc899c466b700c775f1cdac1cde1bcf38ddde677d95' 
  AND token = 'TWyji2qQPunBwxOJbew9/lh/Xa939IQXq10LmDocnoc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}