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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'edcb6e2f7e7055d6c91fa367da66a9e46491a390774f07a2327602c600070ff1' 
  AND token = 'FTZB+OhPtc6Gt/LIr0yY5Q9UM//PyPjtcOa2PGBYm8Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}