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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c46642319646135f97ceef5bdf567f3e8dd1df80de749156ab64f077457043a5' 
  AND token = 'hCC0jb4O9Yp9QHDB5mcXIo9vSb/rCP17Gcr8uzCyIcM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}