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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b816edcc03e4dcdea188aa27ea74d6b4bc6b2ec9c6084c56ec6853c25ad368af' 
  AND token = 'kDz6Skc28yZQ3rRL4TOF7dsY3Mk03jW0VDYH0VrIZdQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}