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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e939553904085a890ba7cb2c858c086e5df57bbde89f4f0aceb1d3b3efee2a06' 
  AND token = 'O75hMpLIACVqJnl0aK/DsFPg8uBeumMC9DT8kAtaM8M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}