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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4741907e84173357b2a6e42dfd716cb34f5ff3cd2ed7e4557359033cc5771269' 
  AND token = 'Ak1uMMbjsw6Lggd8F+qBeuTx30mjBYORJ4HA4daXbQE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}