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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e39390e3011ed8c045e9e6ca52fd4bbe1d83b4b0ee1d3d445a82d9e2b31a6377' 
  AND token = '8m1nOVq80HW0WjQex9e1cHQVFq7wLsAtaT6kpD7TqzM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}