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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b26b06453ae35e43a70828589537ee7e2868e61eef0bbd3ea570e487e7d5d005' 
  AND token = 'QnQRp9HVJsex3ENrCYIGat3jCWrGkd0+9Q9mUKmWDGk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}