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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '99d6fcdddde971479c394fb9ec741ce7af11764fa370be4ccc7556a668b9c293' 
  AND token = '2M42cPoZJbjagTkkeThrYfjh94WC9Q3wbH4s2XyvJKs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}