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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ffbcae9888797ee415abc22c2d14d2ae6288c3809cec31efc9cfb59e9b2c4dc' 
  AND token = 'x54gKoUSeTUaDbGUx9/vTWMbBkXWcZUhoR4OREwHGwE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}