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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '787f5fcf1ba1e3583b5f12cf49d2cd63ddf40532fd557869566cc1014dc7a237' 
  AND token = '1cQVJ+DhVkl4tHS5Y0IxE36stUHjIW7S005e+7qs49Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}