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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46583d7d2cd4a3ed59ae321bd5f194dfb19d4082b02eb30590c565ca09303a73' 
  AND token = 'Ryv1Q2qLxco/oXTuN2QNEEo3Dg089JNY+Jv59k7Tp+o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}