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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '24a4733b36217dc94c9f5de7da567a5e38aca022619ddf7db9f6e6c571eeee2a' 
  AND token = 'lpSS3xVo6Q2dIYAFn8Pztl56RHsb2zo7chR4+ckB5Nw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}