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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7168b7b93c42d116f01a1db5b87f2f96479f6cdffeaa9f435247f5aba5b0ba63' 
  AND token = 'FE4CZbLggCpJTef2Tgf0+LdniWZ7x9CwWhz9xPNQNwM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}