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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd46fdfc42786a09f2b9ad8528ad3b3d68f77502e588dbafbfb56c984dc409eea' 
  AND token = 'bXhNA66jAu4dhjwYDqiMPAQ0JZxLZzuuv/8Hu10OcZE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}