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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b7e43b3188631fcf1e8a57a67a5038df34985003efbb3fee6e11131f7b96f5b9' 
  AND token = 'V9oY8GNh30ipuaR2k3gw85wZ2naFp+mgFHqf6UKS3Mg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}