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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a301b3e66b997195ea6e1eb2c89dd5a51d92cec7b717fdda4f9d0a4a1a6e447d' 
  AND token = '8SPDCc5Q65kK+E/TJrYziAF52TcpZJ7l7QCbJpcKBOw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}