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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4638bf34d1d78d180965f4ef44a0f15845a95fd28a073afaf8a8ec8b33b8258f' 
  AND token = 'ZP3+p7Entw7VIJyemlvhHZIJv/5AlW3IVnD09ik7ERk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}