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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e391f075e2a90d132a1491ab12297f156bf88975e05c5342fd06f5582cb1a5bf' 
  AND token = 'CXskx5QmrqantCWXi5c5HvNbnFHbHwqN5Mv6zW8dXf0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}