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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '578e1db1664e516351c5bdf5e2cfdd37705a28d284e46a94a64d410daddd227a' 
  AND token = 'Yjogh+IRkjLTP+k3gJ8TC47smupTCho0nZUh/uiRk9c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}