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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9d49037312ab575f8340d7b8a6155fc0f0718acd306ca7f01838f86b47023da5' 
  AND token = 'j5jqXgYAMxcjjFKRM8e4sd6OBzpP/ftkzTM4igIOUIk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}