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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ae3a4b214ed6383c01172710e6da1e2bb5d39c80aaf21bb9c1b01d766891f0d0' 
  AND token = 'S4TCRMsn/bMv7dBHhAopcZhZcnfcWQPlAqqZC02XINs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}