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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '445f8809ee3a868d26f3f490c51f8883aef260e9a5489b55c36a0b30e343e7c7' 
  AND token = 'Zn0RQ6uNvMAxOqozZ0Vs5Eh4ffjZGFl6vTlPK4THmAs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}