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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3abecbf05fee4396e3a45587a7b10eb4e9130e4990bcf8f65c4e66409e529348' 
  AND token = 'qM0FvX0Kb1qPF0STGRxXEm10Pl4iKGxxJiS1xzICgtY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}