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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1cab26bc7018033903eb4cb798bd6624222b2e88f199e2e3767440cfe65208cb' 
  AND token = 'Vc073kYI49WLFb4HZiXu8bVnFL4/iLWAMy80ymNfzzM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}