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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c80f7f6e60a369ab9727320f78508020edff20fdd150e222c5bfe40bae7649fd' 
  AND token = 'O7bR/ZSDrIQQnSIch5lZOViQfXzWGZ3fo0+crG7heMw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}