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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f185d92d1fed505e8e176868a31a4d81813ccc6218994e03698c7a42f9505142' 
  AND token = 'w343dCCUjI4fV78bBhupBtri7VyKXETl3/iL3e8TV88=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}