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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44901976881a0cf3bbc9dbaf380817ea3d1c29936488f600145872388213a440' 
  AND token = 'Enytxx37jl2eSx3pagjENKwTRK6OZYRzv/A4zEZvj3I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}