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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f566d18504d93a7ef31b7e97757b865e18a962b6e8cf80ff414bdc4c4ebf8b43' 
  AND token = 'u4h5pKnygp/7kWW7PL/sXrGviV9eSUvCSxiwyFmMcGo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}