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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4467f820122d980af162968b36cf7aec0715a7318757bf4591e755e8287ef681' 
  AND token = 'E7geowoCK7+3xQqSmq80euMyEQMKAgFS41E87Dvrys0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}