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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ffefe342f333afdef0e40f3edb79fb45088229b596669b85a3c792e14e82ba4e' 
  AND token = 'qZHzZZ2gXX2GAoKAER+89948Owt7s0VZ6REXK5r7FeA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}