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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e22410528927f28f278250db23b4bde6c90a1db2553ad78558a6b2d94a3f942' 
  AND token = 'oXtq8Yc2xXkcA3zCBZ6qdW7BI8v4F8MxpNka0PGIZIA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}