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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f28934731cd81277dd1eff4467db67563061f88d740f14d149ca7f4f65c49067' 
  AND token = '/IM3tDF26TiCILNd44SeN+w+xT9At+tXvnjeGlqHN0Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}