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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '327189f39b045b1ffcf22c427c11a6b9dda259e374c0ae37f8c34391fa245b00' 
  AND token = 'DX1uj9l24esHeY8Al6SpiDn+44TFDBxw0nBcHCQALnc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}