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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01ed94b48268d29b031927fa2a36370d29bb8288124d661a35ac1de8b6f28657' 
  AND token = 'kbuh8MX9NdtJs4XKbcg6uNm13yHsgF0SHdwqJiJMOZU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}