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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd80e73d0767ceb4d788fe904a8b58fb55f002b893badcf16b35ab599836c13de' 
  AND token = 'kmdYnORGlT/gk9qXjw2g8PsuIIkES6dWryYXrnK4inE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}