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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b3e18200473e1f297be66a69bbf6996383a8b1fd0b4de3c861c3ef9c158fa543' 
  AND token = 'oX5XPiBuNRJdp5Y9zosQK6hEGcAtg5yinZ9Jm8BECcE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}