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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4439e6adcb3ea47f540a181078c845a4853a5c6dc4d440ef62adc77c59133ce8' 
  AND token = 'aErLV+hczXCJQG2MZDYXI/dPoMpwY3gNc9iZsXrbPDQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}