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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aeb72bceb363b3cd2556c094aab82d0203decdf9f3c3e91f31b060ee635fca22' 
  AND token = 'Eq7B6KKBPiwo/yXwwZIt13EgT4eD4YkoAVt/6wE8phg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}