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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '58d65d28a25a78d932fbe7be3764149ca2963b4fc3cabb4c96b13916c15932c9' 
  AND token = 'lbaVIy/NdlWOY5SFbe1WLbpxM8l6Y/o5oLuxPXDZ5vk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}