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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f625efb16899ebd52f64c670daab470ccf63ea94d2c17a513f109834951f6445' 
  AND token = 'Ya/F6r4Vk/pGVwQl2WO4rCkjeMTHnyqkoXjUJYfn8C8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}