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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '388f98a2799acc2cf2bb34487c1ffe94d2f59ab9a4c46b597d2f8e43a854ae0b' 
  AND token = '3rtvZb0Fzrq+Tn2CjXK4XB/9R0eg9LdIbjk9uEKl3So=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}