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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64b59fcba8ffe870a89df349ff5b4756aab4c43e4a74b19bdffa12aa6520bdac' 
  AND token = 'H9iRL1umJsiANFUT5b6MVo/+PogPwSalT0A/Oa9tSkk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}