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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c4f66b7a0dbc42de49a712b89293d1d8b07c87d04b2e4b5575d373b0c7b7307' 
  AND token = 'DgHxLb5ANU10CE+SFyHxafNFi2WBbwjUfy9RIFE6AmI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}