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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '87a2aa68603236c07fe84ff7c9a2994ddad704271082f57ca4f83241f155bc50' 
  AND token = 'nWMkf/zryL+MFdqjG160zGKBN1dzuG53IoussVIAGwA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}