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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5fab85076964d1b9d1cb4b8be9a67055b778084ce3d5150d65b48502986a53b4' 
  AND token = 'ElmNSL1b09uN4U0u6radC19dWIkpDa5bJ6+RP5TXcMQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}