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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a27dd6aea408286e443588f55d8907fe8ca48c47630a9bb87822088b76ca652' 
  AND token = 'TCQ0o8/HBmozeQwAnZfOmCq84Yrn164KQqMOYSA4JX8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}