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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac787e7b36c353ee03e6e5a322c8e3c0da2fb5aa14decae31330b65daff34672' 
  AND token = 'R4Wq2M8wgyR0FJn31SXL/FxA6rgzKvF8MuwvqyIwVt8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}