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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c109eed66394ae50d7862fdcc4b99990920a6533ec5916c55f968652d4a68103' 
  AND token = 'xhB1qfL8CLwOsAUIee2+lrvI6mO4Z23430pKnznUEJs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}